Job Details

Associate Scientist - Protein Therapeutics

Gilead Sciences currently has an exciting opportunity for a highly motivated associate scientist to join our protein purification, QC, and logistics group within the Protein Therapeutics Department. The successful candidate is expected to work independently and display professional judgment in all aspects of daily research and presentations. This person will work in collaboration with research project teams to generate and validate potential therapeutic proteins and surrogate tool molecules.

Responsibilities

• Perform protein purification, QC, and sample bank registration to support the preclinical development of biopharmaceutical programs across multiple therapeutic areas
• Prepare technical reports, quantitative analyses, and summaries for entry into Excel, PPT, and ELN formats
• Use good oral and written communication skills to relay scientific data
• Actively participate in group meetings, present the results of one's work, interpret data, and draw conclusions regarding presented material and maintain awareness of cutting‑edge technical developments and scientific knowledge and apply these where possible to improve process efficiency

Education and Experience

BS in Biology, Biochemistry, Chemistry or related field with at least 4+ years of relevant experience (6+ years preferred) OR MS with at least 2+ years of relevant experience (3+ years preferred) with below listed characteristics and techniques for the position.

Required skills

• Strong background in protein sciences and protein biochemistry
• Direct industry experience in purifying and characterizing a variety of recombinant proteins, particularly monoclonal antibodies and next generation biologics (e.g., bispecific antibodies, immunocytokines)
• Hands‑on experience in purification techniques including affinity, ion exchange, size exclusion, hydrophobic interaction chromatography using Akta Avant/Pure or BioRad NGC
• Proficiency with various analytical protein characterization techniques such as SEC‑HPLC or UHPLC, SDS‑PAGE, Endosafe
• Ability to perform method development and write protocols
• Proficiency in editing and writing AKTA methods using Unicorn software
• Detailed record‑keeping is a must
• Ability to multi‑task and work in a fast‑paced team environment
• Must be team‑oriented, professional, hard‑working, and interested in learning new skills
• Experience in executing complex experiments to support projects with the ability to troubleshoot and solve problems under guidance
• Ability to analyze and present experimental data with proper software and other necessary tools

Preferred skills

• Experience in protein characterization technologies such as DLS, SEC‑MALS, LC/MS, CE‑SDS, and IEX/HIC‑HPLC would be a strong plus
• Experience in protein formulation leveraging automated liquid‑handling systems such as the BigTuna would be a plus