Job Details

Base Pay Range

$130,000.00/yr - $150,000.00/yr

Location

San Francisco, CA

Seniority Level

• Mid-Senior level

Employment Type

• Full-time

Job Function

• Finance and Accounting/Auditing

Prellis Biologics uses proprietary technology to 3D print lymph node organoids, which we are using to generate in vitro antibody libraries and in vitro human lymph node co‑cultures for generating antigen‑specific B‑cells. We are seeking a skilled and mission‑driven Accountant to join our team and support our financial operations.

Position Summary

The candidate will be responsible for the financial health of our organization, ensuring accurate and transparent financial reporting, compliance with regulations, and strategic financial planning. This role will manage day‑to‑day finances, implement budgeting processes, and provide critical financial insights to support the organization's mission. The ideal candidate is a detail‑oriented, strategic thinker.

Key Responsibilities

• Manage all day‑to‑day accounting operations, including general ledger, accounts payable/receivable and payroll.
• Prepare accurate and timely financial statements, including balance sheets, income statements, and cash‑flow reports.
• Prepare financial reports for the Board of Directors and senior leadership, providing actionable insights.
• Budgeting & Forecasting
• Prepare for and participate in weekly budget meetings with upper management.
• Develop financial forecasts and monitor budget performance, identifying variances and recommending corrective actions.
• Compliance & Risk Management
• Ensure compliance with all federal, state, and local regulations, including tax filings and audits with understanding of GAAP accounting.
• Help monitor internal controls to safeguard organizational assets and mitigate financial risks.
• Strategic Financial Planning
• Assist the COO and operations team to develop long‑term financial strategies aligned with the organization's mission.
• Analyze financial data to support program expansion and operational scalability.

Qualifications

• Bachelor's degree in Accounting, Finance, or related field; CPA highly desired.
• Minimum of 5‑7 years of progressive financial management experience.
• Strong knowledge of accounting principles.
• Prior experience with a Big Four accounting firm or comparable public accounting environment is highly desirable.
• Proficiency in accounting software (e.g., QuickBooks, Bill.com) and advanced Excel skills.
• Excellent analytical, problem‑solving, and communication skills.
• Ability to work in a fast‑paced environment and manage multiple priorities effectively.
• Experience with specific Biotech is a plus.
• General self‑starter with a willingness to collaborate across departments.

About Prellis

Prellis Biologics is a pre‑IPO biotech located in Berkeley, CA with a team‑oriented, inclusive, and family‑friendly culture. Our growing pipeline targets high unmet patient needs across therapeutics including metabolic, inflammation, and oncology disease. Prellis has raised funding from top investors, including Celesta, Khosla Ventures, SOSV, and Avidity Partners.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.

Actual salary will vary based on several factors including but not limited to relevant skills, experience, and qualifications.

Benefits

• A competitive employee benefits package, including group medical, dental and vision coverage, life and disability insurance, flexible spending accounts and a 401(k) plan.
• Stock‑based long‑term incentives.
• Holiday package including a 1+ week winter shutdown.
• Flexible work models, including remote and hybrid working arrangements, where possible.

Prellis does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Prellis Bio is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams—grounded in a wide range of expertise and life experiences—and work even harder to ensure those teams thrive in inclusive, growth‑oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.