Job Details

Overview

Join to apply for the Senior Scientist, Product Development role at Natera

Position Summary: Natera is a global leader in cell-free DNA testing. We measure fetal, tumor, or donor cfDNA at the molecular level to help inform personalized health care decisions with a non-invasive test.

We are looking for a highly motivated Senior Scientist with a strong focus on reagent and process optimization to join the Early Cancer Detection product development team, joining a group of scientists who are tasked with developing and advancing Natera's oncology product portfolio. The Senior Scientist will be working with internal cross functional teams to develop IVD products. The ideal candidate is a driven professional who maintains broad knowledge of molecular biology and chemistry, and applies statistical principles to experiment design and analysis. The Scientist should have an in-depth understanding of design control methods and experience with current NGS oncology diagnostics devices. We are looking for a meticulous and proactive scientist with experience in both NGS-based assay development under design control and meant for submission to FDA and other regulatory bodies and who can work effectively in a fast-paced environment to ensure that the highest quality clinical assays are developed and launched for our patients.

Primary Responsibilities

• Design, develop and validate automated high-throughput NGS assays that will be run in a commercial CLIA laboratory
• Manage assigned technical projects and associated timelines and deliverables in NGS-based assays. Mentor and manage the functional activities of junior employees
• Design and execute moderate to high complexity experiments and perform basic data analysis (e.g. JMP, R, Excel)
• Collaborate with other assay development scientists on the specifications of assay, reagent, equipment and quality metrics for future production assays
• Work with Clinical Laboratory and Quality Assurance to ensure that developed methods meet Natera's rigorous quality standards
• Coordinate with multiple internal groups (automation engineering, laboratory operations, bioinformatics, statistics, project and product management) and serve as point person to ensure the successful identification and timely execution of projects
• Write project protocols, reports and SOPs and train lab operations operators on protocols
• Lead verification activities
• Identify areas for continuous improvement and actively contribute to the effort of introducing better practices to improve production workflows and shorten TAT for patient samples
• May manage Research Associates

Qualifications

• BA/BS with 8+ years experience, MS with 5+ years or PhD with 3+ years experience in assay development and automation for the life science industry.
• Demonstrated track record of development and validation of automated protocols for CLIA labs
• Experience with IVD product development and design controls

Knowledge, Skills, And Abilities

• Strong understanding of the chemistry underlying nucleic acid extraction, PCR, NGS library preparation, and hybrid capture technologies
• Hands-on experience in reagent preparation and quality control for NGS-based assays
• Experience implementing, optimizing, and troubleshooting high-throughput automated assays utilizing liquid handler robots
• Strong individual contributor as well as dedicated team player
• Experience designing and executing studies including stability, guard banding, reproducibility and repeatability and QC method development
• Data analysis (JMP) required, coding skills (Python or R), and liquid handler programming experience are a plus
• Excellent communication, organizational, record-keeping, planning, attention to detail and time management skills
• Ability to manage multiple priorities in a fast-paced, dynamic environment and to collaborate cross-functionally with other groups (regulatory affairs, CLIA, LIMS, lab operations QA, automation, research)

Compensation and Location

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

San Carlos, CA

$125,300—$156,600 USD

What We Offer

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

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Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For More Information

• BBB announcement on job scams
• FBI Cyber Crime resource page