Job Details

Senior Scientist: Data Analytics and Pharmacometric Modeling

Join Amgen's Mission of Serving Patients

At Amgen, our shared mission—to serve patients living with serious illnesses—drives all that we do. We've helped pioneer the world of biotech in our fight against the world's toughest diseases.

As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Senior Scientist - Data Analytics and Pharmacometric Modeling

What You Will Do

In this vital role you will be part of Amgen's Clinical Pharmacology, Modeling and Simulation (CPMS) department focusing on use of data science and predictive analytics methodologies to support drug development via pharmacometric and quantitative systems pharmacology modeling.

You will be responsible for designing and executing an integrated predictive analytics strategy to complement the pharmacometric modeling to make robust inferences to support clinical drug development across diverse therapeutic areas.

Responsibilities:

• Designs modeling and simulation and analytics components of clinical drug development plans and provides expertise to project teams.
• Responsible for planning the analyses to integrate knowledge of pharmacokinetics, pharmacodynamics, patient characteristics and disease states to optimize doses, dosage regimens and study designs.
• Contributes to the analysis of in-vitro and pre-clinical PK/PD data for selection of first in humans (FIH) dose levels and to IND submissions and documentation of appropriate reports.
• Makes recommendations for clinical doses and dosing algorithms to the clinical and Development teams and in regulatory documentation.
• Influences external environment through methods such as publication and presentations.
• Responsible for communicating with partners to ensure appropriate support for programs and studies.
• Provides leadership, guidance and advice in own field, and develops innovative and creative output based on interpretation and analysis.

What We Expect Of You

We are looking for a scientist with these qualifications.

Basic Qualifications:

• Doctorate degree or Master's degree and 3 years of relevant experience or Bachelor's degree and 5 years of relevant experience.

Preferred Qualifications:

• PhD in Statistical and Data sciences, Computer Science, Pharmaceutical Sciences, Engineering, or related fields.
• 3+ years of experience in the life sciences, Biotechnology/Pharmaceutical Industry, consulting or post-doctoral training.
• Demonstrated experience with scripting and implementing data analytics algorithms and models.
• Knowledge/Experience in the usage of machine learning/AI tools in life science area(s) and handling life science datasets is preferred.
• Experience in PK/PD modeling and population-based analyses/simulations with established track-record of model-based drug development in multiple therapeutic areas will be an advantage.
• Excellent interpersonal, technical, and communication skills to lead cross-functional teams.
• Previous record of scientific contributions through peer-reviewed articles and external presentations.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.