Job Details

Research Assistant II Therna Biosciences RNA Design. By Intelligence.

  2025-10-21     MBC BioLabs     San Francisco,CA  
Description:

Overview


We are looking for a creative, driven, and collaborative Research Associate to join our R&D team. This role offers the opportunity to work on cutting-edge RNA technologies and contribute to the development of high-throughput discovery platforms. The ideal candidate brings strong molecular biology skills and a passion for innovation in RNA therapeutics. Reports to: Director of Translational Research


Responsibilities



  • Perform molecular and cell biology experiments in support of platform discovery efforts.

  • Assist in the design, execution, and troubleshooting of experiments involving genomics tools in cell and animal models.

  • Maintain detailed experimental records and contribute to data analysis and interpretation.

  • Participate in the management and organization of laboratory supplies and the logistical operations of the lab.

  • Collaborate closely with team members across functional areas in a fast-paced environment.


Desired experience and skill set



  • Bachelors degree with 3+ years or a Masters degree with 1+ years of relevant laboratory experience.

  • Hands-on experience in mammalian cell culture, molecular cloning, in vitro transcription (IVT), flow cytometry, luciferase reporter assay, Immunocytochemistry (ICC), RNAScope, and western blot.

  • Animal handling experience including injections, blood collection, and tissue processing including IVIS imaging desired.

  • Experience with Massively Parallel Reporter Assays (MPRAs), using either reporter expression or NGS as readout desired.

  • Familiarity with single-cell RNA sequencing workflows (e.g., 10x Genomics), including sample prep and library generation.

  • Exposure to CRISPR-based functional genomics screens is a plus.

  • Strong problem-solving skills, attention to detail, and scientific curiosity.

  • Ability to work both independently and as part of a collaborative, interdisciplinary team.


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