Job Details

Overview

Associate Scientist/Scientist role at Preventive Medicine. Hands?on experimentalist to accelerate next?generation gene editing programs. Title calibrated to experience (Associate, Scientist, Sr. Scientist).

Responsibilities

• Plan, perform, and troubleshoot prime and base editing experiments in mammalian cells.
• Design guides, donors, and constructs; execute cloning, PCR/qPCR, and relevant molecular assays.
• Maintain and passage cell lines; perform transfection/electroporation; establish or edit stable cell pools or clones.
• Quantify and characterize editing outcomes; optimize protocols for editing efficiency, specificity, and off?target assessment.
• Contribute to lab operations (ordering, inventory, equipment maintenance, EHS compliance).
• Stretch: single?cell transcriptomics sample prep/analysis, protein purification/engineering, animal model generation in partnership with in vivo teams.

Required Qualifications

• BS or higher in a relevant field (experience emphasized).
• 2+ years industry experience in biotechnology.
• Demonstrated gene editing experience with next?generation platforms (prime and/or base editing).
• Strong molecular biology skills (cloning, PCR/qPCR, gel/amplicon prep).
• Proficiency in mammalian tissue culture, sterile technique, and basic cell?based assays.

Preferred Qualifications

• Depth in single?cell RNA?seq sample prep, library construction, and/or data interpretation.
• Protein purification (chromatography techniques) and/or protein engineering (construct design, stability/activity optimization).
• Gene editing to generate animal models (design, screening, validation in collaboration with in vivo teams).
• Previous startup environment experience (fast cycles, evolving priorities, cross?functional collaboration).