Job Details

Head of Computational Biology

  2025-09-17     Samplinghuman     Berkeley,CA  
Description:

Job Post Title
Head of Computational Biology

Estimated Base Salary
Market rate, Offers Equity

Employment Type
Full-time

Job Functions
Science, Research

Skills
Data science, Pattern Recognition, Computational Biology, Analytical skills, Machine Learning, Applied Math, Statistics

Seniority Level
Director

The Role

We are looking for a senior data scientist with a strong technical background to lead our advanced algorithms team. You will translate product concepts into technical problem formulations and guide your team of data scientists and ML engineers in developing and productionizing solutions. The ideal candidate has great mathematical intuition, deep knowledge of single cell/spatial omic data, and experience in implementing modern computational tools.

What you will be working on
  • Lead creative vision of our computational platform in coordination with C-suite.
  • Formulate complex clinical problems into solvable algorithmic challenges.
  • Lead development of new analytical methods and multimodal data integration.
  • Increase computational performance, accuracy, and scalability of our platform.
  • Seek actionable insights and ontological frameworks using novel approaches.
  • Help identify and source diverse training data for developing predictive models.
  • Establish rigorous validation frameworks and benchmarks.
  • Stay at the forefront of advances in single-cell and spatial omics data science.
What you should know or have
  • PhD or MS in Computer Science, Machine Learning, or related field.
  • 5+ years of experience analyzing single-cell and spatial sequencing data.
  • Track record of developing data pipelines for single-cell/spatial sequencing.
  • Experience in developing advanced algorithms including deep learning, probabilistic modeling, and unsupervised learning techniques.
  • Creative problem-solving abilities and ability to steer direction of multidisciplinary teams of scientists and engineers.

Sampling Human is introducing single-cell and spatial sequencing solutions for clinical applications. Were revealing a new layer of biological information that enables earlier, more precise insights and drives longer, healthier lives. Our products combine genomic measurements with AI-generated biology in end-to-end data pipelines that redefine whats measurable at scale.

Were a small, well-funded, mission-driven team of molecular and cell biologists, software and automation engineers, mathematicians, computer scientists, and business professionals, all building at the convergence of computation and biology. At Sampling Human, youll do foundational work, chase ambitious ideas, and deliver products that directly impact health. Youll also get access to a cutting-edge tech stack and proprietary datasets that uncover the most interesting cells in the human body at scale.

If you want to build human informatics from the ground up, you are in the right place.

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