Job Details

Head of Biostatistics

Location: South San Francisco, CA (On-site, 4 days/week)

Compensation: ~$300K-$320k base + bonus + stock options

Type: Full-time

About the Role

Our client, a clinical-stage precision oncology biotech, is searching for a Senior Director of Biostatistics to lead the Biometrics function and support the development of novel oncology therapeutics. The company is well-capitalized (over $1B in cash), with multiple programs under internal control, and strong momentum including recent Fast Track designation.

You'll work in a high-performance, highly collaborative environment with a strong succession track—this is a strategic leadership role with future elevation potential. The position reports into a leader who is respected, focused, and known for execution excellence.

Key Responsibilities

• Serve as Biostatistics lead for development programs across all clinical phases.
• Oversee internal/external teams and ensure quality statistical deliverables.
• Contribute to protocols, SAPs, CSRs, publications, and regulatory submissions.
• Provide statistical expertise and drive innovation in trial design and data interpretation.
• Represent Biostatistics with external partners, vendors, and regulatory agencies.

What You Bring

• 15+ years of statistical experience in drug development, 10+ in oncology.
• Hands-on experience with protocol writing, SAPs, and regulatory filings.
• Track record of successful oncology drug approvals.
• Strong leadership, mentoring, and communication skills.
• A preference for early-stage oncology experience is key.

Why Apply

• Competitive comp: base ~$300K-$320k + 25% bonus + 30,000 stock options
• High-impact work on cutting-edge oncology programs
• Transparent, hardworking, and no-fluff culture
• Career growth potential into executive leadership
• Relocation support included