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Director, Strategic Sourcing and Supplier Management

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Director, Strategic Sourcing and Supplier Management

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Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

Revolution Medicines is seeking a motivated individual with a scientific background to play a critical role as the strategic sourcing and supplier management lead for drug product and finished product within the Pharmaceutical Development and Manufacturing (PDM) function. This position will be responsible for business and technical operations in support of PDM outsourcing activities and leading strategic initiatives to enable planning, sourcing, production, and delivery of Revolution Medicines' drug supply, with focus on drug product and finished product. This role is an individual contributor with cross-functional team leadership responsibilities, reporting into the Director, Strategic Sourcing and Supplier Management.

Responsibilities:

• Responsible for ongoing management of RevMed's global network of Drug Product Manufacturers.
• Drive implementation of RevMed's CMO Lifecycle Management Program across our network of Drug Product CMOs. Support identification, selection, on-boarding, start-up and ongoing management of CMO's.
• Lead CMO management activities, including business and manufacturing support, issue resolution, and performance management. Lead weekly cross-functional site leadership team meetings with CMO to ensure all start-up and production activities are conducted successfully on-time.
• Understand CMO partner internal structure and processes and work with team to ensure successful production, issue resolution and communication takes place to meet Mirati's production requirements.
• Lead site issue management and resolution during routine production and escalate issues, when appropriate. Drive risk management activities, including the identification of risks and creation of mitigation plans. Support product transfer activities to the CMO.
• Establish and maintain effective relationships with key CMO stakeholders to ensure successful manufacture and issue resolution across the external manufacturing network. Foster collaborative relationships with internal stakeholders (e.g. Clinical Operations, Development, Regulatory, Quality, Operations, Finance, etc.) to understand organizational needs.
• Create and manage contracts, requests for pricing, supply agreements, etc. Ensure activities are executed in alignment with established Supply and Quality Agreements. Work with stakeholders and suppliers to help drive business issues to resolution. Understand contractual / financial implications of issues and solutions and ensure appropriate outcomes are implemented. Manage and communicate forecasts to the sites. Support capacity planning activities.
• Manage CMO Performance. Measure and report on the overall performance of each CMO. Identify and drive performance improvements (COGS, cycle time, quality, etc.) to ensure efficient, reliable supply of all clinical and commercial products.
• Work collaboratively with Project Management to ensure projects from conception to implementation and close-out, as directed by management.
• Serve as Revolution Medicines' primary business operation lead and project management interface between internal PDM functions and CRDMOs for drug product and finished product by providing adequate oversight.
• Ensure projects/programs meet desired results, compliance, speed, quality, and cost.
• Support cross-functional CRDMO management activities, covering all aspects such as business needs identification, market screening, contracting, vendor qualification and set-up, compliant delivery of services, and discontinuation.
• Work with PDM senior management and cross-functional teams to assess and manage supplier performance through use of personal influence, internal business review meetings, and/or joint governance meetings.
• Identify and deliver on cost savings opportunities.
  
  

• B.Sc. or M.Sc. in scientific field with 15+ years of experience in pharmaceutical strategic sourcing and/or supply chain.
• Experience working with domestic and international CRDMOs.
• Experience managing both strategic and tactical/operational projects.
• Working knowledge of and experience in clinical manufacturing, regulatory, QA, and cGMP requirements for small molecules.
• Working knowledge of small molecule drug development and commercialization, including, but not limited to, oral solid dosage form development and manufacturing, scale-up, and validation.
• Working knowledge of pharma end-to-end supply chain, with oral solid dosage form related supply a plus.
• Strong negotiation skills.
• Solid project management, facilitation, and problem solving skills.
• Solid organizational and time management skills.
• Effective, open, and transparent communication skills (verbal and written).
• Capable of working on multiple projects/tasks and able to meet timelines.
• Self-starter with a high-level of comfort with ambiguity and complexity and the ability to multi-task while consistently delivering quality results.
• Team-oriented, progressive thinker who enjoys participating in an innovative and creative work environment.
  
  

• Experience in implementing and/or managing inventory management system.
• Working knowledge of commercial manufacturing.
• Experience developing, negotiating, and executing clinical or commercial supply and/or quality agreements.
  
  

The base salary range for this full-time position is $204,000 to $255,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy . For additional information, please contact ...@revmed.com .

Seniority level

• Seniority level

  Director

Employment type

• Employment type

  Full-time

Job function

• Job function

  Purchasing and Supply Chain

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